Tritium and Carbon-14 Radiolabels Services
Radio Tag method enables the efficient radiolabeling of large protein-based molecules with Tritium or Carbon-14, revolutionizing the field of pharmacokinetics (PK) investigations.
In the dynamic landscape of life sciences research, the demand for reliable radiolabeling services is paramount. Radiolabeling, particularly utilizing Tritium (3H) and Carbon-14 (14C), facilitates the precise tracking and understanding of molecular processes, aiding advancements in drug development and environmental studies. At the heart of our radiolabeling services lies the innovative RadioTag method. This groundbreaking technique enables the efficient radiolabeling of large protein-based molecules with Tritium or Carbon-14, revolutionizing the field of pharmacokinetics (PK) investigations.
Key features of the RadioTag method
Single Protocol Versatility
The RadioTag method boasts a single protocol applicable to a wide range of large molecules. This versatility streamlines the radiolabeling process, enhancing efficiency and reducing turnaround times for PK studies.
Covalent Radiolabeling Technique
Utilizing a covalent radiolabeling technique, RadioTag directly targets lysine residues or N-terminal amino groups in proteins and peptides. This precise targeting ensures optimal labeling efficiency while minimizing unwanted modifications to the target molecules.
Molecular Weight Flexibility
From small peptides to large protein complexes exceeding 350 kDa, the RadioTag method accommodates a wide range of molecular weights. This flexibility enables comprehensive studies across various biological systems, facilitating a deeper understanding of drug behavior and interaction dynamics.
Minimal Protein Modification
Our company prioritizes the preservation of biological activity during radiolabeling. The RadioTag method minimizes protein modification, mitigating potential negative effects on target binding and overall biological function. This commitment to maintaining the integrity of biomolecules underscores our dedication to delivering high-quality radiolabeling services.
Applications of the RadioTag method
The versatility of our company's radiolabeling services extends to a myriad of applications, including:
Pharmacokinetic Studies
Radiolabeled compounds serve as invaluable tools in elucidating drug absorption, distribution, metabolism, and excretion (ADME) profiles. Through precise PK studies, our clients gain crucial insights into drug kinetics and bioavailability, guiding informed decision-making throughout the drug development process.
Tissue Distribution Analysis
Quantitative whole-body autoradiography (QWBA) and micro-autoradiography (mARG) techniques enable detailed analysis of tissue distribution patterns. By radiolabeling biologics, our company facilitates comprehensive tissue distribution studies, providing invaluable data for assessing drug localization and potential toxicity profiles.
Metabolism Studies
Understanding the metabolic fate of drugs and compounds is essential for predicting their efficacy and safety profiles. Our company's radiolabeling services support metabolism studies, enabling the identification and characterization of metabolites through radiotracer analysis.
Tritium and Carbon-14 radiolabeling services offered by our company represent a cornerstone in life sciences research. Through our expertise in synthesis, application, and innovation, we empower researchers and industry professionals to unravel the complexities of molecular processes, driving forward advancements in drug development and environmental studies. Contact us today to discuss your research needs.
Trust Us for Your Radiolabelling and Radiosynthesis Needs.
Our company offers a comprehensive range of tritium and Carbon-14 radiolabels services to support a wide range of research and development efforts in the pharmaceutical, biotechnology, materials science and chemical industries.
Please kindly note that our products and services are for research use only.
