Comprehensive In vitro ADME Studies
The absorption, distribution, metabolism, and excretion (ADME) of a drug are pivotal determinants of its efficacy and safety profile. At our company, we leverage state-of-the-art in vitro assays to assess the ADME properties of drug candidates with precision and reliability. Our assays cover physical-chemical properties, drug absorption and transport mechanisms, metabolism pathways, and potential drug-drug interactions. Through meticulous analysis, we empower clients to make informed decisions regarding candidate selection and optimization, expediting the drug development process.
In vitro Toxicity Assessment
Ensuring the safety of drug candidates is paramount in pharmaceutical research. Our company's in vitro toxicity assessment services enable thorough evaluation of potential adverse effects, mitigating risks associated with drug development. Our comprehensive liver toxicity packages encompass both general and mechanistic toxicity evaluations, providing insights into hepatotoxicity early in the development process. Additionally, we offer assays for assessing phototoxicity, cardiotoxicity, and genotoxicity, employing robust methodologies to identify and mitigate safety concerns effectively.
In vivo Pharmacokinetics Profiling
Characterizing the pharmacokinetic profile of a drug in vivo is essential for understanding its behavior within biological systems. Our company's in vivo pharmacokinetics studies offer valuable insights into drug formulation, absorption, distribution, metabolism, and excretion. Through meticulous analysis of tissue distribution and metabolite quantification, we provide comprehensive data to inform dosing regimens and optimize therapeutic outcomes. Our expertise extends to specialized pharmacokinetic studies, enabling tailored solutions to meet the unique requirements of each drug candidate.
