Carbon-14/Tritium Bioanalysis Services
- Discovery and Preclinical Carbon-14/Tritium Bioanalysis
- Clinical Carbon-14/Tritium Bioanalysis
Harnessing the unique properties of Carbon-14, which undergoes radioactive decay over time, bioanalytical scientists can trace the fate of a drug molecule from absorption to excretion, unraveling its metabolic pathways and interactions within biological systems. This meticulous analysis not only sheds light on the efficacy and safety of potential therapeutics but also guides critical decisions in drug design, dosing regimens, and clinical trial strategies.
Our company harnesses a diverse array of platforms and techniques to empower our bioanalytical endeavors. From traditional chromatographic methods such as HPLC and UPLC to advanced technologies including Liquid Scintillation Counters (LSC) and LC+AMS, our arsenal of tools enables us to navigate the complexities of Carbon-14 bioanalysis with unparalleled precision and efficiency.
Our Services
At our company, we recognize the pivotal role of accurate and reliable bioanalytical data in elucidating the pharmacokinetic and metabolic profiles of pharmaceutical compounds. Our Carbon-14 bioanalysis services encompass a spectrum of capabilities meticulously designed to meet the evolving needs of drug discovery, preclinical, and clinical stages. Our services include:
Discovery and Preclinical Carbon-14/Tritium Bioanalysis
Clinical Carbon-14/Tritium Bioanalysis
Discovery and Preclinical Carbon-14/Tritium Bioanalysis
- In the nascent stages of drug development, our expert team specializes in crafting tailored solutions to unravel the intricate pathways of drug metabolism and distribution. Leveraging cutting-edge technologies such as High-Performance Liquid Chromatography (HPLC) and Ultra-Performance Liquid Chromatography (UPLC), we develop selective methods for the quantification of parent Active Pharmaceutical Ingredients (APIs) and their metabolites.
- Moreover, our proficiency extends to the realm of imaging-based quantification techniques, including Quantitative Whole-Body Autoradiography (QWBA) and Micro-Autoradiography (MARG), enabling precise localization and distribution analysis of radioactive materials within tissues or cells. With a meticulous approach, we navigate through diverse matrices, encompassing animal samples and various in vitro settings, to facilitate comprehensive metabolism studies and metabolic profiling.
Clinical Carbon-14/Tritium Bioanalysis
- Our adept team orchestrates the development and validation of selective HPLC or UPLC methods for both parent APIs and metabolites, ensuring the utmost accuracy in quantification.
- Furthermore, our capabilities extend to ultrasensitive bioanalysis through Liquid Chromatography coupled with Accelerator Mass Spectrometry (LC+AMS), enabling the precise quantification of trace levels of Carbon-14. This sophisticated approach caters to the burgeoning demand for clinical 14C-microtracer studies and low exposure 14C-material analysis, underlining our dedication to advancing drug development with unparalleled precision.
Clinical Carbon-14/Tritium Bioanalysis
- Central to our ethos at our company is a steadfast commitment to regulatory compliance and adherence to industry standards. Our bioanalytical methods and sample analyses adhere rigorously to the guidelines outlined by regulatory bodies such as the FDA, EMA, and ICH, ensuring the reliability and integrity of the data generated.
- Moreover, our state-of-the-art facilities, equipped with Liquid Handling Automation Stations and a GLP/GCP compliant facility for LC-MS/MS sample analysis.
Our company is a leading supplier of carbon-14/tritium bioanalysis services that meet the evolving needs of drug discovery, preclinical, and clinical stages. If you are interested in our services, please do not hesitate to contact us.
Trust Us for Your Bioanalysis Needs.
Our company offers a comprehensive range of carbon-14/tritium bioanalysis services to support a wide range of research and development efforts in the pharmaceutical, biotechnology, materials science and chemical industries.
Please kindly note that our products and services are for research use only.
