Custom Synthesis
Our company specializes in the custom synthesis of chiral molecules, tailoring solutions to meet precise project requirements. Whether enantiomeric pure compounds, chiral intermediates or APIs, our skilled team ensures high-quality products with superior purity and efficacy.
Chiral synthesis includes a variety of methods designed to selectively produce the desired enantiomers or diastereomers. These methods include:
Chiral Pool Synthesis
Using readily available enantiomeric pure starting materials such as amino acids or sugars, chiral library synthesis can effectively construct complex chiral molecules, making it a preferred method for certain applications.
Biocatalysis
Biocatalysis uses enzymes or living cells to catalyze chiral transformation efficiently and selectively, providing a sustainable and environmentally friendly solution for chiral synthesis, effectively addressing racemic intermediates.
Enantioselective Catalysis
Enantioselective catalysis using chiral coordination complexes or organic catalysts can precisely control stereochemistry and promote the synthesis of highly selective complex chiral molecules.
Organocatalysis
Organic catalysis uses small organic molecules as catalysts to accelerate chiral transformation and obtain a variety of chiral compounds through asymmetric synthesis.
Process Development
Our company specializes in process development services, a key aspect of chiral synthesis, which involves optimizing synthesis routes and improving process efficiency. And through careful experiments and analysis, we can improve the reaction conditions, catalyst selection and purification methods to simplify the production workflow.
- We prioritize scalability and repeatability in process development to ensure a seamless transition from lab-scale synthesis to commercial manufacturing.
- Throughout the process development phase, we use advanced analytical techniques to monitor reaction progress, characterize intermediates and assess product purity.
Analytical Support
In chiral compound synthesis, rigorous analytical support is essential to ensure product quality, purity and consistency. Our company provides comprehensive analytical support throughout the chiral synthesis process, from characterization of starting materials to analysis of final products.
- Using cutting-edge instruments such as high-performance liquid chromatography (HPLC), gas chromatography (GC), nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS), we offer comprehensive analytical services tailored to the unique requirements of chiral chemistry.
- In addition, our analytical support team conducts thorough characterization of chiral compounds, including troubleshooting, impurity analysis and stability testing. Whether solving formulation challenges or investigating differences between batches, our team takes a systematic approach to solving problems.
Chiral Separation & Resolution
Our company specializes in chiral separation and resolution techniques to isolate enantiomers and diastereomers with high purity and selectivity. Whether clients require resolution of racemic mixtures or purification of chiral compounds, we offer efficient and reliable separation methods tailored to meet specific project needs.
