Peptide Synthesis
From short oligopeptides to long polypeptides, our company can synthesize peptides up to 200 amino acids in length. Utilizing proprietary ligation technology, we guarantee a success rate of over 98%. From milligram to kilogram scales, we offer scalable synthesis solutions to accommodate projects of varying scope and complexity.
Synthesis methods
Our synthesis methodologies encompass liquid-phase peptide synthesis, solid-phase peptide synthesis, as well as combined solution and on-resin peptide synthesis techniques.
Peptide types
- Isotope-labeled peptides
- Phosphopeptides
- Macrocyclic peptides
- Lipidated macrocyclic peptides
- Disulfide bond peptides
- Glycopeptides
- Special amino acid peptides *
* Enantioselective synthesis of various unnatural amino acids and incorporation of them into peptide sequences.
Peptide Modification
Our company offers an extensive repertoire of over 250 peptide modifications, ranging from terminal adjustments to conjugations and labeling. Our modification services are meticulously tailored to align with the diverse exigencies of biomedical research and drug development.
Terminal Modifications
Our terminal modification suite includes acetylation, amidation, fluorescent labeling, and biotinylation, among others.
Amino Acid Substitutions
We proffer a comprehensive library of unusual and modified amino acids, encompassing D-amino acids, β-amino acids, and methylated amino acids, empowering researchers to design peptides endowed with bespoke properties and functionalities.
Conjugations and Labeling
Our portfolio encompasses a broad spectrum of conjugation and labeling options, including protein conjugation, dye labeling, and isotope labeling, facilitating versatile applications in various research domains.
Glycopeptide Modifications
We offer glycopeptide synthesis services encompassing N-linked glycopeptides, O-linked glycopeptides, and C-linked glycopeptides, fostering innovative avenues in drug discovery and therapeutic research.
Peptide Analysis & Purification
- Equipped with an array of specialized analytical instruments, our laboratories facilitate meticulous purity control, enabling precise monitoring and evaluation of peptide purity levels to uphold stringent quality benchmarks.
- Our purification strategies are thoughtfully devised, leveraging a fusion of separation techniques tailored to exploit the physicochemical properties of peptides, thereby ensuring purification to the requisite levels for specific research or therapeutic applications.
Peptide Libraries
In the realm of high-throughput screening and drug discovery, our company offers peptide library synthesis services. Our peptide libraries encompass diverse peptide sequences, enabling researchers to explore structure-activity relationships and identify lead compounds for further development.