Oncology Models

Large Cancer Cell Line Bank

At the core of our company's oncology disease models is its extensive cancer cell line bank, comprising over 2,000 validated cell lines. These cell lines represent various cancer types, subtypes, and genetic profiles, providing researchers with a robust platform for preliminary screening and mechanistic studies.

Validated Cell-Line Derived Xenograft (CDX) Models

Our company's 1,000+ fully validated cell-line derived xenograft (CDX) models serve as invaluable tools in preclinical oncology research. These models, derived from established cancer cell lines, closely mimic human tumor behavior, aiding in the evaluation of drug efficacy, pharmacokinetics, and pharmacodynamics.

Patient-Derived Xenograft (PXD) Models

A standout feature of our company's oncology disease models is its collection of over 300 patient-derived xenograft (PXD) models. These models are derived directly from patient tumor samples, retaining the original tumor characteristics, genetic heterogeneity, and treatment responses. Coupled with detailed patient histories, PXD models offer a personalized and clinically relevant platform for drug testing and translational research.

Specialized Synthetic Tumor Models

Our company's innovation extends to specialized synthetic tumor models, encompassing over 80 models with complete immune profiles and standard of care (SOC) data. These models not only represent tumor cells but also incorporate immune cell components, reflecting the complex tumor microenvironment crucial for immunotherapy and combination therapy studies.