Integrated Drug Discovery Services
- Antiviral Therapies
- Central Nervous System (CNS) Disorders
- Cardiovascular Diseases
- Gastrointestinal Disorders
- Immune Disorders
- Inflammation and Pain
- Oncology
- Respiratory Diseases
Integrated Drug Discovery encompasses a comprehensive array of services and disciplines, ranging from target identification and hit-to-lead optimization to preclinical candidate selection and beyond. This approach fosters seamless collaboration between various scientific disciplines, including medicinal chemistry, computational biology, in vivo and in vitro pharmacology, and structural biology, among others. By integrating these diverse expertise areas, our company can help you to streamline the drug discovery process, expedite decision-making, and enhance the overall efficiency of therapeutic development.
Disease Areas
Leveraging our multidisciplinary expertise and advanced technologies, our company specializes in integrated drug development across several key therapeutic domains, including:
Antiviral Therapies
Central Nervous System (CNS) Disorders
Cardiovascular Diseases
Gastrointestinal Disorders
Immune Disorders
Inflammation and Pain
Oncology
Respiratory Diseases
Antiviral Therapies
Our company's integrated drug development services encompass the discovery and optimization of novel antiviral agents, targeting viral pathogens with precision and efficacy. Through a combination of computational modeling, medicinal chemistry, and in vitro pharmacology, we expedite the identification of promising antiviral drug candidates, paving the way for the development of next-generation therapies to combat viral infections.
Central Nervous System (CNS) Disorders
Our company's integrated drug development services focus on advancing therapeutics for CNS disorders, including neurodegenerative diseases, mood disorders, and neurodevelopmental disorders. Through a comprehensive approach that integrates target validation, lead optimization, and preclinical evaluation, we accelerate the discovery and development of innovative treatments to improve cognitive function, mood regulation, and overall neurological health.
Cardiovascular Diseases
Our company's integrated drug development services specialize in cardiovascular research, offering tailored solutions for the identification and optimization of therapeutics targeting heart disease, hypertension, and vascular disorders. Through a combination of computational biology, structural biology, and in vivo pharmacology, we expedite the discovery and development of cardiovascular therapies aimed at reducing the burden of cardiovascular disease and improving patient outcomes.
Gastrointestinal Disorders
Our company's integrated drug development services focus on advancing therapeutics for gastrointestinal disorders, including inflammatory bowel disease, irritable bowel syndrome, and gastrointestinal cancers. Through a comprehensive approach that integrates molecular biology, pharmacology, and translational sciences, we accelerate the discovery and development of innovative treatments to alleviate symptoms, reduce inflammation, and restore gastrointestinal health.
Immune Disorders
Our company's integrated drug development services specialize in immune disorder research, offering tailored solutions for the identification and optimization of immunomodulatory therapeutics. Through a combination of immunology, pharmacology, and biomarker analysis, we expedite the discovery and development of novel treatments to restore immune balance and improve patient outcomes in immune-mediated diseases.
Inflammation and Pain
Our company's integrated drug development services focus on advancing therapeutics for inflammation and pain management, offering tailored solutions for the identification and optimization of analgesic and anti-inflammatory agents. Through a comprehensive approach that integrates pharmacology, medicinal chemistry, and biomarker analysis, we expedite the discovery and development of novel treatments to mitigate pain, reduce inflammation, and enhance patient quality of life.
Oncology
Our company's integrated drug development services specialize in oncology research, offering tailored solutions for the identification and optimization of anticancer agents. Through a combination of molecular biology, pharmacology, and translational sciences, we expedite the discovery and development of novel treatments to target cancer pathways, inhibit tumor growth, and improve patient outcomes in oncology.
Respiratory Diseases
Our company's integrated drug development services focus on advancing therapeutics for respiratory diseases, offering tailored solutions for the identification and optimization of respiratory therapies. Through a comprehensive approach that integrates respiratory biology, pharmacology, and translational sciences, we expedite the discovery and development of novel treatments to alleviate symptoms, improve lung function, and enhance patient outcomes in respiratory diseases.
Workflow
Target/Hit Identification
The drug discovery journey begins with target identification, where our company employs advanced techniques such as protein science and crystallography to identify promising biological targets. Through fragment screening using Surface Plasmon Resonance (SPR), we identify hit compounds that interact with these targets, setting the stage for further optimization.
Hit to Lead (H2L) Optimization
Once hits are identified, our team of experts applies medicinal and computational chemistry techniques to optimize their properties, transforming them into lead compounds. Through iterative design, synthesis, and testing, we enhance potency, selectivity, and other desirable characteristics, paving the way for lead optimization.
Lead Optimization
With a focus on medicinal chemistry and Drug Metabolism and Pharmacokinetics (DMPK) studies, our company further refines lead compounds. Structural biology tools, including co-crystallization and computational modeling, assist in optimizing the compounds' interactions with their targets, ensuring safety and efficacy.
Candidate Identification/Selection
After lead compounds are optimized, the candidate selection process begins, leading to the identification of Investigational New Drug (IND) candidates. This entails process development, scale-up, GLP API supply, genotoxicity, and toxicity studies, culminating in the selection of promising drug candidates poised for clinical development.
Our company is a leading supplier of integrated drug discovery services, offering a comprehensive suite of solutions tailored to the diverse needs of the pharmaceutical industry. Through our advanced technologies, expert teams, and collaborative approach, we are committed to advancing pharmaceutical innovation and driving the development of life-changing therapeutics. Contact us today to discuss your needs.
Trust Us for Your Integrated Drug Discovery Needs.
Our company offers a comprehensive range of integrated drug discovery services to support a wide range of research and development efforts in the pharmaceutical, biotechnology, materials science and chemical industries.
Please kindly note that our products and services are for research use only.
