Large Molecule Bioanalysis Services
- Monoclonal Antibodies (mAbs)
- Antibody Drug Conjugates (ADCs)
- Fusion Proteins
In the dynamic landscape of pharmaceutical and biotechnological research, the analysis of large molecule therapeutics stands as a critical pillar in drug discovery and development processes. Our company, a distinguished service provider with over two decades of experience in the life sciences industry, offers cutting-edge large molecule bioanalysis services tailored to meet the evolving needs of our clients.
Types of Large Molecules
In the intricate world of large molecule bioanalysis, the diversity of analytes spans a broad spectrum of therapeutic modalities, each with its unique structural and functional properties. Our company specializes in providing advanced bioanalytical services tailored to the analysis and characterization of various classes of large molecules including the following.
Monoclonal Antibodies (mAbs)
Antibody Drug Conjugates (ADCs)
Monoclonal Antibodies (mAbs)
Our company excels in the bioanalysis of mAbs, offering precise quantification and characterization services to support preclinical and clinical studies. By leveraging advanced analytical techniques such as ligand binding assays (LBA) and liquid chromatography-mass spectrometry (LC-MS/MS), we provide valuable insights into the pharmacokinetics, pharmacodynamics, and immunogenicity profiles of mAb therapeutics.
Antibody Drug Conjugates (ADCs)
Our company specializes in the bioanalysis of ADCs, offering comprehensive services for quantifying both the antibody and payload components in complex biological matrices. Our expertise in ligand binding assays (LBA) and hybrid LC-MS/MS approaches enables accurate assessment of ADC pharmacokinetics, target engagement, and payload release kinetics, facilitating the optimization and development of ADC-based therapies.
Fusion Proteins
Our company specializes in the bioanalysis of fusion proteins, providing comprehensive services for quantifying and characterizing these complex molecules. Through advanced analytical techniques such as LC-MS/MS and cell-based assays, we elucidate the pharmacokinetic, pharmacodynamic, and immunogenic properties of fusion protein therapeutics, enabling informed decision-making in drug development.
Analytical Approaches
With a focus on advanced analytical approaches, we offer tailored solutions to meet the diverse needs of drug discovery and development programs.
Ligand Binding Assays (LBA)
At our company, we leverage advanced LBA platforms, including enzyme-linked immunosorbent assays (ELISA) and electrochemiluminescence assays (ECLA), to quantify large molecules in biological matrices with exceptional accuracy and precision.
Liquid Chromatography-Mass Spectrometry (LC-MS/MS)
Our company utilizes state-of-the-art LC-MS/MS systems coupled with advanced sample preparation techniques to achieve accurate and reproducible results in pharmacokinetic and pharmacodynamic studies.
Cell-Based Assays
Our company offers a wide range of cell-based assays, including receptor binding assays, cell proliferation assays, and neutralizing antibody assays, to evaluate the efficacy and safety of large molecule drugs in vitro.
Biomarker Analysis
Our company specializes in biomarker discovery and validation, utilizing cutting-edge technologies such as mass spectrometry and next-generation sequencing to identify and quantify biomarkers in clinical samples.
Our company, with its expertise and technological capabilities, is dedicated to providing high-quality bioanalysis services tailored to the unique needs of our clients in the pharmaceutical, biotechnological, and academic sectors. Contact us today to discuss your needs.
Trust Us for Your Bioanalysis Needs.
Our company offers a comprehensive range of large molecule bioanalysis services to support a wide range of research and development efforts in the pharmaceutical, biotechnology, materials science and chemical industries.
Please kindly note that our products and services are for research use only.
